

BIOL 111 General Biology I Exam III Review Fall 2001
Chapters 10 - Basic Principles of Heredity (3 lectures)
- Distinguish between the following:
- P generation F1 generation and F2 generation
- dominant and recessive
- gene and allele
- heterozygous and homozygous
- genotype and phenotype
- autosome and sex chromosome
- dominance and incomplete dominance
- dihybrid and monohybrid crosses
- Describe test cross, true-breeding, and locus.
- Invent a phenotype for R and for r. Assuming that R is dominant over r, use a Punnett
square to predict the phenotypes and genotypes resulting from a cross between the
following: RR and RR, RR and rr, Rr and Rr, rr and Rr, rr and rr.
- Invent a phenotype for T, t, O, and o. T is dominant over t and O is dominant over o and
they are on separate chromosomes (They show independent assortment). Use a Punnett square
to predict the phenotypes and genotypes resulting from a cross between TtOo and TtOo.
- Explain the effect of two genes being linked on the same chromosome.
- Explain how there can be new combinations of genes on the same chromosome.
- Describe how gene maps are created.
- How do chromosomes determine sex in mammals?
- Hemophilia is a recessive X-linked gene. Use a Punnett square to predict the phenotypes
and genotypes resulting from a cross between the following:
XHXH x XhY, XHXh
x XHY, XHXh x XhY
- Explain the significance of dosage compensation and Barr bodies.
- Compare sex-linked and sex-influenced traits.
- Invent a phenotype for M1 and for M2. Assuming that M1
and M2 exhibit incomplete dominance, use a Punnett square to predict the
phenotypes and genotypes resulting from a cross between the following: M1M1
and M2M2, M1M2 and M1M2,
M2M2 and M1M2, M2M2 and
M2M2.
- Describe an example of: multiple alleles, pleiotropy, epistasis, polygenes, inbreeding,
and hybrid vigor. How do each of these affect the patterns of inheritance?
- Complete the Post-Test questions 2-8, 11 and 12.
- Answer the Review Questions 1-5, 7-9, 11-13, and 15.
Chapter 11 DNA (2 lectures)
- Explain what is meant by the one gene-one enzyme hypothesis.
- Describe the experiment by Griffith. What did we learn from it?
- Describe the life cycle of a virus or bacteriophage.
- Describe the experiment by Martha Chase and Alfred Hershey. What did we learn from it?
- Describe the contributions of Rosalind Franklin, James Watson, and Francis Crick toward
understanding the structure of DNA.
- Describe how adenine, guanine, thymine, cytosine, sugar, and phosphate are arranged in
the DNA molecule.
- Describe how DNA is replicated (copied).
- Describe how DNA is organized into chromosomes.
- Answer Post-Test questions 1 and 3.
- Answer Review Questions 1-6.
Chapter 12 RNA and Protein Synthesis (2 lectures)
- Compare DNA and RNA.
- Compare DNA replication and RNA transcription.
- Describe the materials and events involved in transcription.
- Describe the materials and events involved in translation.
- Invent a sequence of bases for a strand of DNA. Write out the complementary strand of
DNA. Write out a mRNA strand copied from the first DNA strand. What anticodons on tRNA's
would stick to this mRNA? What amino acids does your DNA code for?
- In eukaryotes, there is posttranscriptional modification and processing. Explain where a
cap, poly-A, introns, and exons fit into this.
- What does it mean that the genetic is nearly universal?
- Describe the genetic code.
- Give examples of how base substitution mutations, nonsense mutations, and frameshift
mutations in the DNA could affect the proteins coded for.
- Answer questions 1-3, 6 and 10 in the Post-Test.
- Answer Review Question 1.
Last updated 22 October 2001 fast@sxu.edu

Saint Xavier University, Dale Fast, General Biology I